A diacetyl-induced quiescence in young Caenorhabditis elegans
Identifieur interne : 000798 ( Main/Exploration ); précédent : 000797; suivant : 000799A diacetyl-induced quiescence in young Caenorhabditis elegans
Auteurs : Maria Christina Hoffmann [Canada] ; Laurie H. L. Sellings [Canada] ; Derek Van Der Kooy [Canada]Source :
- Behavioural brain research [ 0166-4328 ] ; 2010.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Many organisms enter quiescence in response to adverse environmental factors. Here, we show that L1 stage C. elegans entered a quiescent state after 3 hours exposure to diacetyl in which movement and growth stopped for hours to days after odorant removal. Entry into quiescence was dependent on neurons affected by the osm-3 mutation, and by AWA neurons. Conversely, AWB/AWC neurons, the guanylyl cyclase ODR-1, and the TRPV-channel subunit OCR-2 inhibited entry into Ll arrest. This quiescent behavior represents an alternative use of olfactory signaling pathways besides approach or avoidance, and is a novel model in which to characterize genes implicated in quiescence.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000168
- to stream PascalFrancis, to step Corpus: 000207
- to stream PascalFrancis, to step Curation: 000609
- to stream PascalFrancis, to step Checkpoint: 000173
- to stream Main, to step Merge: 000804
- to stream Main, to step Curation: 000798
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">A diacetyl-induced quiescence in young Caenorhabditis elegans</title><author><name sortKey="Hoffmann, Maria Christina" sort="Hoffmann, Maria Christina" uniqKey="Hoffmann M" first="Maria Christina" last="Hoffmann">Maria Christina Hoffmann</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Sellings, Laurie H L" sort="Sellings, Laurie H L" uniqKey="Sellings L" first="Laurie H. L." last="Sellings">Laurie H. L. Sellings</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Van Der Kooy, Derek" sort="Van Der Kooy, Derek" uniqKey="Van Der Kooy D" first="Derek" last="Van Der Kooy">Derek Van Der Kooy</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">10-0424921</idno><date when="2010">2010</date><idno type="stanalyst">PASCAL 10-0424921 INIST</idno><idno type="RBID">Pascal:10-0424921</idno><idno type="wicri:Area/PascalFrancis/Corpus">000168</idno><idno type="stanalyst">FRANCIS 10-0424921 INIST</idno><idno type="wicri:Area/PascalFrancis/Corpus">000207</idno><idno type="wicri:Area/PascalFrancis/Curation">000609</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000173</idno><idno type="wicri:doubleKey">0166-4328:2010:Hoffmann M:a:diacetyl:induced</idno><idno type="wicri:Area/Main/Merge">000804</idno><idno type="wicri:Area/Main/Curation">000798</idno><idno type="wicri:Area/Main/Exploration">000798</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">A diacetyl-induced quiescence in young Caenorhabditis elegans</title><author><name sortKey="Hoffmann, Maria Christina" sort="Hoffmann, Maria Christina" uniqKey="Hoffmann M" first="Maria Christina" last="Hoffmann">Maria Christina Hoffmann</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Sellings, Laurie H L" sort="Sellings, Laurie H L" uniqKey="Sellings L" first="Laurie H. L." last="Sellings">Laurie H. L. Sellings</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Van Der Kooy, Derek" sort="Van Der Kooy, Derek" uniqKey="Van Der Kooy D" first="Derek" last="Van Der Kooy">Derek Van Der Kooy</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Molecular Genetics, University of Toronto</s1><s2>Toronto, M5S 3E1</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author></analytic><series><title level="j" type="main">Behavioural brain research</title><title level="j" type="abbreviated">Behav. brain res.</title><idno type="ISSN">0166-4328</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Behavioural brain research</title><title level="j" type="abbreviated">Behav. brain res.</title><idno type="ISSN">0166-4328</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Behavior</term><term>Caenorhabditis elegans</term><term>Development</term><term>Neuron</term><term>Olfaction</term><term>Plasticity</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Neurone</term><term>Olfaction</term><term>Développement</term><term>Comportement</term><term>Plasticité</term><term>Caenorhabditis elegans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Many organisms enter quiescence in response to adverse environmental factors. Here, we show that L1 stage C. elegans entered a quiescent state after 3 hours exposure to diacetyl in which movement and growth stopped for hours to days after odorant removal. Entry into quiescence was dependent on neurons affected by the osm-3 mutation, and by AWA neurons. Conversely, AWB/AWC neurons, the guanylyl cyclase ODR-1, and the TRPV-channel subunit OCR-2 inhibited entry into Ll arrest. This quiescent behavior represents an alternative use of olfactory signaling pathways besides approach or avoidance, and is a novel model in which to characterize genes implicated in quiescence.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Hoffmann, Maria Christina" sort="Hoffmann, Maria Christina" uniqKey="Hoffmann M" first="Maria Christina" last="Hoffmann">Maria Christina Hoffmann</name></region><name sortKey="Sellings, Laurie H L" sort="Sellings, Laurie H L" uniqKey="Sellings L" first="Laurie H. L." last="Sellings">Laurie H. L. Sellings</name><name sortKey="Van Der Kooy, Derek" sort="Van Der Kooy, Derek" uniqKey="Van Der Kooy D" first="Derek" last="Van Der Kooy">Derek Van Der Kooy</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/OcrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000798 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000798 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= OcrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:10-0424921
|texte= A diacetyl-induced quiescence in young Caenorhabditis elegans
}}
| This area was generated with Dilib version V0.6.32. |  |